 Tissue Engineering Skin
- Product Name: Tissue Engineering Skin
- Trade Name: ActivSkin
- Registration Certificate: No.3461110, 2007, SFDA (Permitted)
- Production Standard: YZB-0698-2005
- Production Certificate: No.3283, 2005, FDA of Shaanxi
Ten Characteristics of Tissue Engineering Skin
TE processes and isolates donor skin tissues to obtain pure epidermal and fibroblast cells, which will then go through a scale-up culture and amplification process to form a kind of new TE skin tissue（including epidermis and dermis）. Thus, TE skin almost has a similar structure to the natural normal human skin with dermal and connective tissues.
· Adapt to various skin defect
Activskin can be used to repair skin defect caused by different kinds of matter such as burn, ulcer, and trauma and so on, and it be used by the patients in different ages. Also it can be used in examination and selection of medicine and cosmetic. In addition to these, it can be a good facility of cell biology, molecular biology, pharmacology, genetics and other life sciences research in academy.
· Effective and safe
According to the clinical trial observation, the result shows there is no patient appearing adverse reaction. It is fit for all kinds of defected skin treatment. All cases heal up completely, the result clearly demonstrated that ActivSkin promote wound healing up, particularly cut down the average healing time. With the similar structure to normal skin, the ActivSkin can breathe as the normal skin does. Also, it can keep the wound moist, and no stored liquid found on the wound.
· Lowness of immunogenicity
Containing cells that can directly repair the defected skin, ActivSkin can be used for various patients. Via technical management, its antigen is much lower than allogenic skin.
· No need for second surgery, lessening the pain for the patients
For those patients who need skin planting, on the traditional therapy method, autogenic skin has to be cut from the patients, and then transplant it on the wound. The patients have to suffer two times surgery, which would increase the pain of the patients. If using ActivSkin, it will be much easier. Put it on the managed wound, and tie up with gauze without cutting skin from the patients’ body and the second surgery, preventing the patients from more pain.
· Shorten healing up time
Using AcitvSkin can clearly shorten the healing time for repairing the defected skin, and improve the healing quality of the wound. Usually, it need half of the traditional treatment time to heal up. Its fibroblasts can produce fibroblast growth factors, epidermal cells and growth factors, and both of these two factors can promote the growth of dermis and epidermis, sequentially accelerate the tissue regeneration on the defected part, as well as the rapid growth of granulation and new skin.
· Lessen the pain for the patients, and reduce pigmentation
Compared with the traditional treatment, it can reduce the pain for the patients after surgery, avoiding the formation of blain and remains.
· Effectively reduce the formation of scar
The result of clinical trial demonstrates it can reduce the t formation of scar to prevent appearance influence to the patients via using ActivSkin.
· Easy to operate in clinic
The doctors just need to put ActivSkin on the managed wound, and tie up with gauze under pressure without any sewing, numerous medicine changing and inflammation avoiding, so it is as convenient as the ordinary wound tie up.
· Can replace the traditional products and treatment method
ActivSkin is not only easy to operate in clinic but also has notable effect. With production technology and strict quality standard that SFDA stated, it is more convenient, advanced, scientific, and guaranteed than those nonstandard traditional treatment methods, so it can be the substitute of those traditional treatment methods for treating the skin defect caused by burn, ulcer, trauma, or other matters.
· Promising market prospect
According to the statistics of some Chinese authorized institutes, there are about 15 million patients with burn and ulcer each year, and 10 million of them need skin transplant. 388 million cm2 skin is demanded (which is equal to five football court). All the expense would be 53.5 billion RMB. Taking up just 2% of the market, we would achieve the sales scale of 1 billion. Its market capability and prospect is very broad.
Production Standard of Tissue Engineering Products
Production Standard of Tissue Engineering Skin YZB-0698-2005
Take the leading State Standard of TE Skin Classification Criteria
Part 4 of Tissue Engineering Medical Products: The Terminology and Classification of Skin Substitute was carried out on 1st, Jan, 2008.
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